Aptamer-Based Sensors for Thrombin Detection Application

Thrombin facilitates the aggregation of platelet in hemostatic processes and participates regulation cell signaling. Therefore, development thrombin sensors is conducive to comprehending role course a disease. Biosensors based on aptamers screened by SELEX have exhibited superiority for detection. In this review, we summarized aptamer-based detection which rely specific recognitions between aptamer. Meanwhile, unique advantages different including optical electrochemical were also highlighted. Especially, these electrochemistry potential be miniaturized, thus gained comprehensive attention. Furthermore, concerns about detection, prospects future promising avenues field presented.